Evaluation of the Anti-ulcer Effect of Extra Virgin Avocado (Persea americana) Oil in Rats

Peptic ulcer disease is a gastrointestinal disorder of high mortality and morbidity. Therapy this condition with conventional drugs presents therapeutic challenge due to incidents unwanted side effects, the cost these medications. The use products from natural sources will provide useful alternatives their minimal being inexpensive, readily available, especially in resource-challenged nations continent Africa other developing economies. Oils derived plants are increasingly used management several conditions. This study aims at evaluating antiulcer activity extra virgin avocado oil rodents using ethanol-induced, indomethacin-induced models. Test group was given (1ml per 250g weight) for 7 days before induction ulcer. Positive controls received omeprazole 30 mg/kg, while negative control animals were distilled water (10ml/kg) respectively, stomachs excised histopathological examinations carried out. Avocado significantly reduced index both models when compared group, findings corroborate that ameliorates ulcerations present has demonstrated possesses significant activity.